Sustained fluoride-release additive for dental products

Dental caries (tooth decay) results from the de-mineralization of the tooth enamel by acidic fluids. The fluoride ion concentration from a toothpaste or mouthwash has an initial peak that decreases below therapeutic levels one to two hours after application, due to salivary clearance. An approach that provides a sustained constant release of fluoride over longer time periods would be far more beneficial. Our technology is based on a layered double hydroxide (LDH) material that is capable of repeatedly taking-up and releasing fluoride from soluble sources.

As an additive to oral healthcare products the material will provide a sustained release of fluoride, with the fluoride in the water supply, or mouthwashes, acting to re-charge the LDH. It will therefore act as a more effective means of protecting patients from developing carries. The technology is suitable for applications as an additive in consumer dental products such as toothpastes or mouthwashes. Other applications include professional restorative materials such as dental resins, denture bases, orthodontic cements.